80+ Best Isekai Anime With OP MC From a Parallel World

Nowadays, it is not rare to find the best Isekai genre anime when you are surfing the internet. Most series are usually overhyped with trope characters. However, today I have handpicked a fair number of Isekai anime with OP MC who is powerful enough to make the enemy tremble with fear with their unusual power. Let’s stick with these overpowered protagonists as they dominate their respective Isekai worlds. The list might include some of your favorite Isekai anime, so it is time to watch and get nostalgic.

82. Fushigi Yuugi (Mysterious Play)

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In this isekai anime series, Misaka Yuuki is an ordinary junior high school girl who travels to a parallel world called “The Universe of Four Gods.” She meets our OP protagonist Tamahome, a young man with a charming personality.

The MC saves Miaka from a group of slave traders by using his overpowered skills. Through a series of events, Miaka discovers that she is a priestess that can summon a God by gathering seven celestial warriors, and Tamahome is one of them. She must work with him to summon God while finding a way back home.

81. Children of the Whales (Kujira no Kora wa Sajou ni Utau)

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Chakuro, the fantasy series’ main character, lives on a mysterious secluded island called Mud Whale with his best friends. Many people on this island are cursed with supernatural powers known as Samia, and Chakuro is one of them. Our protagonist is pretty powerful; that’s why he is called Destroyer.

One day, he discovers a new island, unlike the others. Upon investigating, Chakuro finds that this island is part of an ancient civilization, and artifacts on this island might help him discover more about his extraordinary power and Mud Whale

80. Hinamatsuri

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Yoshifumi Nitta is a man working for a Yakuza gang to support his family while fulfilling his own dreams. He meets a girl named Hina who suddenly arrives via a space capsule in his house. Later, Yoshifumi finds that Hina belongs to an advanced race from a parallel world, and she ends up here as she left her home because of troublesome adults.

Hina, the OP MC of this fantasy isekai, holds command over various supernatural abilities like telekinesis. However, she must continuously use them, or else she will unleash a deadly explosion. Troubled by this situation, Yoshifumi must let Hina use her powers continuously to avoid a disaster.

79. Kenja no Deshi wo Nanoru Kenja

isekai anime op mc Kenja no Deshi wo Nanoru Kenja

A veteran player whose avatar resembles a cool wizard wakes up in an MMORPG game world. He learns that it has been 30 years since he disappeared and he has turned into a little girl named Mira. He is now tasked with finding nine missing wizards and embarks on a journey to prove his legacy.

78. Battle Girls: Time Paradox (Sengoku Otome: Momoiro Paradox)

best isekai anime with op mc

Yoshino Hide is an average high school girl who finds herself in trouble every time because of her silly behavior. She visits a shrine to pray for success in upcoming exams, but a strange light takes her back in time (Sengoku Era).

The main character Oda Nobunaga turns out to be an overpowered lady skilled in combat; in fact, all historical characters are female in this world. With this situation in place, Yoshino must help her in uniting Japan.

77. Shining Tears X Wind

isekai anime with op mc

Souma Akizuki, is a college student passionate about sports. He discovers “End Earth” from a book that states that it is a parallel world. Together with his friend named Touka Kureha, they began investigating it. They meet Mao, a catgirl from End Earth, and through a series of events, they travel to this parallel universe.

Souma found out about his overwhelming power, which enabled him to draw various swords from the hearts of his beloved ones. Souma is destined to save this world from a space-time monster called Zeroboros.

76. How a Realist Hero Rebuilt the Kingdom (Genjitsu Shugi Yuusha no Oukoku Saikenki)

isekai anime with Op mc

Kazuya Souma, is about to get admission to a university. Still, he is not a bit happy about it because his grandfather just passed away, who was his sole remaining family. In this time of distress, Souma gets summoned to another world in the Elfrieden Kingdom, which is about to collapse because of poor administrative reforms.

He must save this kingdom from demise to get back home. Being a realist, the OP character is ready to implement substantial rational reforms with the help of his newfound companions.

75. My Isekai Life

My Isekai Life

Yuuji Sano works long hours for a company that he knows is not good. One day a strange message appears on his laptop and invites him to another world. At first, Yuuji thinks it’s a virus and ignores it, unaware that this means accepting the invitation – there’s no escaping from an isekai summons!

Before he knows it, he finds himself in an alternate universe with the title of Monster Tamer – the weakest rank of adventurer. Part of Yuuj wonders if this is just a dream caused by being overworked, but he decides to take advantage of his new skills and tames slimes around him which grants him extra power to become a Sage.

However, being an easy-going hero isn’t always straightforward and Yuuji clearly has limited choices in this matter.

74. Combatants Will Be Dispatched! (Sentouin, Hakenshimasu!)

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Kisaragi Corporation plans to conquer all universes, including parallel worlds, using their advanced agents.

It is a comedy isekai with an OP MC named Six. He was selected to carry out this mission along with Alice, an android. They end up traveling to the Grace Kingdom, located on a mysterious planet.

Upon reaching the royal place, they discover the Kingdom is fighting with the demon lord’s army. Because of Agent Six’s foolish mistakes, they are now forced to fight with the army. He must use his so-called overpowered advanced abilities to defeat the minions of the demon lord. However, this task may prove more complicated than they ever imagined.

73. The Familiar of Zero (Zero no Tsukaima F)

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Tristan Magic Academy is famous for producing talented magicians, but one young girl named Louise, studying at this academy is unable to cast magic efficiently. Her magic spells are nothing but disasters.

However, one of her magic spells ends up summoning our MC named Saito Hiraga from the human world. At first, She considers him a mere servant, but later it becomes known that he can use a familiar powerful ability known as Gandalf.

He becomes a true OP Protagonist with the ability to defeat even the most potent foes easily. Louise, together with Saito, might become heroes of this world.

72. Digimon Adventure

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Taichi is not your usual OP MC. The gate to Digimon World has been closed for the entire 3 years, and Taichi Yagami and his friends are now living everyday life. His friends are planning for their future lives, but he is still trapped in his past life, unable to move on.

One day when he finds a rampaging Digimon in his town. Surprisingly, he finds the power to summon his partner named Agumon with the help of his old digital device and defeats the hostile Digimon; after all, he is the legendary Digimon tamer. Taichi decides to contact his friends about it. He might not realize it yet, but Taichi might end up in Digimon World again as something sinister is brewing over there.

71. Kiba

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Zed lives in a fantasy world called “Calm.” The entire world is deprived of freedom because of strict government policies. The world is nothing but hell waiting to suck in as many people as possible.

While running from pursuers, Zed finds a portal to a parallel world and jumps into it, hoping to gain his long-desired freedom and power. He finds himself in the world of Templars, where he must fight other warriors to claim a power that can change the course of different worlds.

He acquires a spirit named Amil Gaoul which can grant him powerful wings. Zed makes his way in this world with his overpowered abilities trying to live a life without any regrets.

70. Endride

best sekai anime with Op mc

Shun Asanaga is a middle school student with a bright personality. One day, he barged into his dad’s office to complain that he didn’t attend his birthday party.

Much to his grief, upon reaching the office, he finds nobody. While leaving, Shun finds himself attracted to a mysterious girl that transports him to another parallel world called Endra.

He meets with Emilio, the prince of Endra, who is planning to overthrow his father’s rule. Shun must use his newly acquired secret power called Warp Relic, which made him overpowered, to help him while searching for a way home.

69. Kami no Tou  

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On a continent filled with darkness lies a tower that summons people from different worlds to conquer it, and in return, the tower will fulfill their every wish.

Twenty-Fifth Baam is a teenager living in a dark cave. He meets a girl named Rachel, who becomes his very first friend, and gradually she pulls him out of the darkness.

Although Twenty-Fifth Baam wasn’t summoned, he still decides to conquer the tower for the sake of Rachel.

At first, isn’t strong enough, but gradually, he becomes powerful through training, and people begin to fear him as an overpowered demon.

68. Jujutsu Kaisen

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The supernatural isekai anime revolves around Curses and how they destroy people’s lives. It begins with the OP MC named Yuuji Itadori, a simple-minded high school student passionate about helping people. Through a series of events, he witnessed a curse that was going to kill his friend. Y

Yuuji destroys the curse by using a cursed item that turns out to be a Finger of a legendary demon king named Sukuna. He gained tremendous power from the finger and became overpowered. Now, Yuuji must join Jujutsu Technical School to control his powers while saving people from more curses.

67. Appleseed: Ex Machina

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In this futuristic isekai cyborgs and advanced pieces of technology are everywhere. Deunan Knute is a young girl who joins the E.S.W.A.T special forces as an agent. She works with her partner named Briareos, a man who turned into a cyborg. His entire body resembles an advanced robot. Together, they execute missions for the safety of Olympus.

Deunan is truly an overpowered character as she excels in every field, whether it is hand-to-hand combat or device manipulations. However, things begin to change in Olympus when a man named Tereus joins their team, who surprisingly has the same appearance as Briareos in human form.

66. Kuma Kuma Kuma Bear

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This next adventure series is very special isekai because it doesn’t focus on an MC that needs physical strength to fight monsters.

Yuna is a teenage girl obsessed with an online virtual reality game called Fantasy World Online. The game creators sent her a gift package to appreciate her contribution to their gamer’s community. Upon unboxing, She finds a cute bear costume and wears it despite feeling embarrassed. She gets summoned to the game world right after wearing it, and to her surprise, she cannot log out anymore.

The bear costume raised her stats and fighting power to the point that she became overpowered. Unable to grasp the situation, Yuna decides to enjoy this world while defeating monsters to level.

65. The Saint’s Magic Power is Omnipotent (Seijo no Maryoku wa Bannou Desu)

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The Kingdom of Salutania suffered from the havoc of deadly monsters that compelled them to summon a Holy Saint from a parallel world to save them.

Sei Takanashi is a mature girl working in a local agency. Upon reaching home, she ends up getting sucked in by a magic portal that takes her to Salutania. Sei was left to her devices despite being summoned a saint because the mage summoned two Saints, and Prince chose the other pretty girl.

Unable to get home, She decides to live and study there. However, Mc’s power might not let her live a normal life.

64. Seirei Gensouki: Spirit Chronicles

isekai anime with op mc

Haruto Amakawa suffers from unrequited love. One day, he gets involved in a bus accident that ends up killing him. Soon after, he finds himself reincarnated in the body of a kid named Rio, living in the slums. He witnesses his mother’s assassination and decides to take revenge. Haruto’s consciousness got combined with Rio, and now he must live as Rio in this world.

He acquires various powers as a powerful spirit dwells in his body which makes him overpowered. Rio must survive in this world while trying to find the whereabouts of the assassins that killed his mother.

63. I’ve Been Killing Slimes For 300 Years And Maxed Out My Level

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This series is a generic isekai where the main character dies and then gets reincarnated in the parallel world.

Azusa Aizawa works in a corporate office. She suffers from the hectic routine of her work which leaves her with no time for rest.

One day, She collapses from overwork and dies, only to be reincarnated in another magical world. A goddess blesses Azusa with immortality, and she begins to live a calm life in this world.

She continues killing low-level monsters like Slimes for almost 300 years and finds that she has become overpowered as she has achieved the maximum possible level in this world. Although this should make her happy, Azusa predicts that her calm lonely life might not remain the same if the word about her powers gets out.

62. The Ambition Of Oda Nobuna (Oda Nobuna no Yabou)

isekai anime with op mc
53. Slimes for 300 Years and Maxed Out My Level

Yoshiharu Sagara is a teenager studying in high school who is obsessed with the warlords of the Sengoku period. He even plays a game centered around this era. One day, Yoshiharu finds himself transported to the past where different warlords were fighting to unite Japan.

To his surprise, all warlords in this world are cute females, unlike the original history. Yoshiharu decides to help Oda Nobuna to achieve her ambition while trying to keep the timeline of this parallel world the same. His knowledge of the history and Sengoku period might prove to be a double-edged sword for Yoshiharu and his newfound fellows.

61. Blood Lad

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The demon world was considered a mere belief, but in reality, it does exist, and powerful vampires and demons rule it. Our protagonist is Staz Charlie Blood, a powerful vampire with overpowered abilities.

Despite possessing the power to rule the demon world, he decides to enjoy a quiet life in his home as an Otaku obsessed with manga and games. He meets a girl named Fuyumi Yanagi, who unknowingly gets into the demon world through a portal.

However, soon she is eaten alive by a monster plant, much to Staz’s dismay. He decides to bring her back to life by any means possible.

60. Mahoutsukai Reimeiki (The Dawn of the Witch)

isekai anime with op mc The Dawn of the Witch

Sable is a young boy who cannot recall anything from his prior life, including why he enrolled in the prestigious Royal Magic Academy of the Kingdom of Wenias. He has been struggling academically and was almost expelled, but is now given another opportunity: to partake in a treacherous special training located in some distant village. His mission is to popularize the utilization of magic across a region that barely recovered from the war between the Church and witches; where magic and its users are still being met with suspicion.

The commencement of the Witch Age rests on Sable’s shoulders, who must prove his worthiness through results at this OP training to graduate.

59. Isekai Yakkyoku

isekai anime with op mc  Isekai Yakkyoku

It’s time to revolutionize medical care in a distant world by utilizing modern medicine! A new spin on the isekai genre has arrived: A scientist named Falma de Médicis specializes in chemicals and medicine passes away and ‘resurrects’ as the ten-year-old son of a royal apothecary in an alternate universe. In this other world, privileged individuals are lavished with treatment while the working class struggles to obtain healthcare.

The protagonist makes it his mission to render health services available for everyone, regardless of their social standing. Furthermore, Falma finds that he can formulate medicines that have never been seen before by imagining the chemical components of elements – so there’s also an element of alchemy included here. With the aid of modern pharmacy and his skill, Falma sets out to cure all maladies around him.

58. Welcome to Demon School! Iruma-kun (Mairimashita! Iruma-kun)

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Iruma Suzuki is a blue-haired guy with a caring personality. His parents sold him to a demon named Sullivan for some money. He is ready to meet his demise, but fortunately, the demon wants to adopt him instead of eating him alive. Iruma is transferred to a school in the demon world to live and study there.

He must live with caution as things will be disturbed if anyone finds out about his race. Iruma learns that living in this new world is not as bad as he imagined despite the problems.

57. To Your Eternity (Fumetsu Anata e)

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A mysterious being from a parallel world ends up on earth without any consciousness but the ability to turn into anything he wishes. Years Later, it takes the form of a dying wolf, and for the first time, it awakened its consciousness.

Our OP Mc is Fushi, a young boy living in a snow-covered land. He dies through a series of events, and the immortal being takes on his appearance and begins to live like him.

Fushi starts traveling the world without any aim. His interaction with other humans might help him understand more about himself.

56. Knight’s & Magic

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This animated Isekai tells the story of the main character Tsubasa Kurata, a teenager obsessed with games and Otaku stuff. He likes to build robots like Gundams. He met his tragic fate when a car crashed, and Tsubasa was caught in it.

He gets reincarnated in a magic fantasy world as Ernesti Echevarria, a young boy with a noble background. He begins to discover the magical things of this world, and giant robots called Silhouette Knights intrigued his curiosity very much to the point he decided to build an original one.

By using his overpowered magical abilities, Ernesti sets out to create a new silhouette knight along with his friends.

55. Marchen Awakens Romance (MÄR)

isekai anime with Op mc

Ginta Toramizu is an otaku kid obsessed with parallel worlds and magic. Since childhood, he firmly believed that such a world existed and would get there one day. Most of his friends laughed at him for having such a pipe dream.

However, Ginta’s long-desired wish is fulfilled when a magic gate appears before him that takes him to Mar Heaven, a magical world with mysterious powers.

He finds Babbo, a magical ARM weapon capable of bestowing the user with unparalleled strength. Upon claiming it, Ginta becomes overpowered. He decides to fight for justice in the upcoming war with this power in hand.

54. Mahou Shoujo Madoka★Magica (Puella Magi Madoka Magica)

isekai anime with Op mc

Madoka Kaname wants to become cool because she believes herself to be useless. Through a series of events, she meets Kyuubey, a cat familiar with the ability to bestow a person with magical powers. He presents her with an offer that she can’t refuse.

She turns into a girl with overpowered abilities who gets to ask for one wish. Later, Madoka discovers that she might have to sacrifice more than she bargained for as the life of a magical girl is filled with nothing but despair.

53. Isekai Nonbiri Nouka (Farming Life in Another World)

Isekai Nonbiri Nouka (Farming Life in Another World)

This farming anime is like watching someone play FarmVille but with cute anime characters and a god-given almighty farming tool. The main character, Hiraku, dies of a serious illness but God takes pity on him and reincarnates him in a fantasy world with his health and youth restored. And the best part? He gets an all-in-one farming tool that can transform into anything he wants. It’s like having the ultimate Swiss Army knife for farming!

The show is so relaxing and heartwarming, I felt like I was there on the farm with the characters. And the food? It looks so delicious! I was salivating every time Hiraku harvested something. The music is soothing, and the animation is breathtaking. It captures the serene beauty of the countryside perfectly.

But let’s talk about the elephant in the room – the harem. I mean, come on, every damn resident in the village is a hot woman who wants a piece of Hiraku. It’s like he’s living in a reverse harem dream world. And he’s OP as hell, so nobody wants to mess with him. It’s hilarious how he’s building his farm, estate, and business empire while also dealing with the ladies.

The plot is a classic slice-of-life, and the events are based on Hiraku’s POV. The subtle but ever-present hints show off his ever-growing vanilla harem, and it’s just funny to see him play Civ 6 while building his farm. The sound and voice acting are great, and the characters are eye-catching (and forgettable, but who cares when you have a harem, am I right?).

52. Saikyou Onmyouji no Isekai Tenseiki

Saikyou Onmyouji no Isekai Tenseiki

Okay, so we’ve got this dude, Haruyoshi Kuga, who’s the strongest exorcist out there. But you know what? That’s not enough for him, he wants more power. So he ends up getting killed by some jealous haters. RIP Haruyoshi, but don’t worry folks, he’s not done yet!

He casts a spell as he dies and bam! He reincarnates as Seika Lamprogue, an illegitimate son of a noble family. But guess what? His new family doesn’t give him the time of day because of his lineage and lack of magic. Poor Seika. But he’s not too bothered because he’s got the knowledge from his past life to help him out. He starts making allies and exploring his abilities, all while avoiding his past mistakes.

Seika is not your typical isekai op protagonist. He’s not a clueless idiot. He remembers everything from his past life and he’s not about to let anyone betray him again. He’s smart, sly, and conniving. He’s not afraid to manipulate or even kill people to get what he wants. It’s refreshing to see an MC who’s not all “morals, morals, morals.”

Of course, there are still your typical isekai tropes, like the childhood friend who’s in love with the MC, magical schools, jealous brothers, and rapey characters who are only there to make you hate them. But you know what? It’s still a fun show.

51. Leadale no Daichi nite

isekai anime with op mc Leadale no Daichi nite

Cayna, who is beautiful and charming, is forced to rely upon her OP powers when she finds herself in the game world after being on life support in the hospital. Her skills make her one of the most powerful characters in Leadale yet she needs to disguise her abilities due to the presence of malevolent forces. Though she attempts to stay unnoticed, Cayna’s extraordinary power astonishes those around her.

50. Dr. Stone

isekai anime with Op mc

Dr. Stone is a sci-fi adventure anime based on the apocalypse manga of the same name. It features a mysterious petrification apocalypse that takes modern civilization back to the stone age.

Senkuu is a high school guy obsessed with science and technology. His craze for science enabled him to perform various science experiments that might not have come out successful, but still, he deserves praise for them.

One day, a green light suddenly overlapped the entire earth and turned mankind into stone. Centuries later, Senkuu breaks out from petrification only to find the world turned into the stone age. His overwhelming knowledge of science and technology is the last resource that can help humanity survive.

49. Chivalry of A Failed Knight

isekai anime with Op mc

The story is set in a parallel world where individuals are born with supernatural abilities that enable them to forge weapons from their souls. They are referred to as Blazers.

This fantasy isekai tells the story of the MC Ikki Kurogane, a kind guy passionate about becoming a Mage Knight. However, he is deemed irregular or a loser in the magic academy because he belongs to the tier F rank of Blazer.

He works hard, trains his skills to the maximum level, and becomes overpowered, now he needs to defeat the all-powerful Blazers to conquer the title of Mage Knight.

48. My Next Life as a Villainess: All Routes Lead to Doom!

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The series’ main character is Caterina Claes, a girl from a noble background. She regains her memory of her past life where she was a shut-in girl obsessed with dating sim gamers, and her current world is similar to a game called “Love Fortune.”

Despite knowing that she will be killed in the end, Caterina decides to change her tragic fate by all possible means.

47. CHOYOYU!: High School Prodigies Have It Easy Even in Another World!

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Prodigies are very rare in all parts of the world. However, Japan has seven young prodigies renowned for their respective skills.

Tsukasa Mikogami, a young intelligent guy, becomes the Prime Minister. Through a series of events, He finds himself in a fantasy world along with six other prodigies. They end up helping the oppressed demi-humans.

Tsukasa must lead the other prodigies to establish their rule while finding a way back home.

46. Life with an Ordinary Guy who Reincarnated into a Total Fantasy Knockout

isekai anime with op mc

Hinata Tachibana and Tsukasa Jinguuji are two childhood friends leading normal lives as office workers. One day, however, they encounter a mysterious being that catapulted them into a strange new world.

Upon arriving, Jinguuji finds his best buddy had suddenly turned into an attractive blonde-haired blue-eyed girl. This striking transformation completely throws him off guard, yet he is determined to keep their friendship intact. For that to happen they have to defeat the demon lord and come back to their old selves as soon as they could.

45. Tsukimichi Moonlit Fantasy (Tsuki ga Michibiku Isekai Douchuu)

isekai anime with Op mc

Makoto Misumi is summoned to a parallel world because his parents made a contract with a Goddess. But the poor guy is rejected by the Goddess, because she, well, finds him ugly and throws him at the end of her world. Ego burn!

But Makoto receives some cool overpowered abilities from a Moon God and decides to take his revenge on the Goddess.

44. Douluo Dalu

isekai anime with Op mc

San Tang is a member of a prestigious martial arts Clan trying to claim a forbidden treasure. He holds command over various martial art styles, including the use of hidden weapons.

Upon stealing the forbidden treasure, He intentionally falls from a cliff only to get reincarnated into a parallel world where people are born with the ability to control spirits.

At first, Tang receives a weak spirit that is considered useless, but upon using his past great knowledge, he can strengthen this spirit to a powerful one. Tang mastered the spirit power and became befitting to be called overpowered.

43. Isekai Cheat Magician

MC Taichi is an ordinary high school guy with a caring personality. On his way to school, a mysterious light transported him to a fantasy world along with his childhood friend named Rin Azuma.

Upon awakening, they face a giant monster, fortunately, a group of adventurers saves them by killing the monster.

Taichi visits the adventurer guild to test his magic abilities. He discovers that he has gained insane powers. Taichi decides to explore this world while finding a way back. However, he might have to face a lot of powerful foes that threaten his life.

42. Log Horizon

isekai anime with op mc

The story is set In Japan, where a virtual reality game named “Elder Tale” is famous enough that millions of people play it regularly.

Our main character is Shiroe, a college student with an introverted personality. He is pretty obsessed as he has been playing it for many years.

Shiroe’s dream of experiencing this game in the real world comes true when he finds himself trapped inside the fantasy game.

Shiroe becomes Elder Tale’s overpowered character who has the best chance to get out of any dangerous situation.

41. Drifters

isekai anime with op mc

The sword anime revolves around the various warriors and their quest to save their new world from mysterious beings called Ends.

The overpowered protagonist is Toyohisa Shimazu, a man obsessed with severing the heads of his enemies. He is a Japanese warrior from the past who was supposed to die in the battle of Sekigahara, but instead of dying, he finds himself transported to a strange world.

Through a series of events, he meets Oda Nobunaga and Yoichi Suketaka Nasu, Japanese warriors from different timelines. He initiates a war against Ends because they oppress the innocent elves living on the continent.

40. Tweeny Witches (Mahou Shoujo-tai Arusu)

isekai anime with op mc

Arusu is a teenage girl who firmly believes in the existence of magic. Through a series of events, Arusu finds herself transported to another world full of magic and wonders.

She discovers that witches rule this world and are pure evil as they enslave spirits. She is determined to use magic for the good of this world and decides to change the way this world works by becoming a witch herself.

38. Problem Children Are Coming From Another World, Aren’t They? (Hepburn: Mondaiji-tachi ga Isekai Kara Kuru Sō Desu yo?)

isekai anime with op mc

MC OP Izayoi Sakamaki is a clever guy with strong psychic abilities. He is implanted with advanced nanomachines, which makes him overpowered. Izayoi, with his friends, was living a boring life on earth.

One day, he receives an invitation to a parallel world called Little Garden. Upon reaching this new world, Izayoi, and his friends find themselves motivated by a game that involves fighting the demon army. They might get to experience their long-desired exciting life in Little Garden.

39. Restaurant to Another World (Isekai Shokudou)

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In a famous shopping district lies a restaurant called Youshoku no Nekoya, famous for delicious meals and mouth-watering appetizers. Everyone loves to have dinner in this restaurant.

However, it has a secret that it serves customers from another world. Moreover, these customers are dragons, elves, demigods, etc. Our protagonist is Master, the owner of this restaurant. He manages the whole restaurant with the help of his loyal employees.

38. BOFURI: I Don’t Want to Get Hurt, so I’ll Max Out My Defense

isekai anime with op mc

If you love watching isekai anime with Op MC with a VR theme, then this one is for you.

Kaede Honjou is a cute teenage girl with a happy-go-lucky personality. She ends up playing a famous virtual reality game called New World Online upon her friend’s suggestion. Kaede uses her all-game points to max out her defenses.

At first, it seemed like a novice mistake, but surprisingly, she is happy with this decision because she has acquired overpowered defensive skills, which will protect her from any damage. Gradually, Kaede becomes a top player in this game without doing much. She must make new friends in this world to experience the real fun of virtual reality games.

37. I’m Quitting Heroing

isekai anime op mc I'm Quitting Heroing

Everyone has the desire to be a hero who can save the world and protect their homeland. Op Mc Leo Demonheart is a brave individual who worked hard to free his kingdom from an odious demon king; however, instead of gaining recognition and admiration, he is completely rejected and all his effort are rendered meaningless. This makes Leo want to quit the heroic occupation.

With nowhere else to go, he is exiled and has no choice but to enlist in the army of his former enemy. But the army is not what it once was before its defeat at Leo’s hands. As a result, Leo must maintain his new position by welding his powers back into OP mode.

36. Btooom!

isekai anime with op mc

Ryouta Sakamoto is obsessed with the famous online game called Btooom! He drops out of high school because of poor grades and becomes a shut-in gamer causing his mother to take a lot of stress.

On his way back from failing an interview, Ryouta is kidnapped by strangers only to find himself stranded on a mysterious island with some other people. Through a series of events, He learned that they are forced to play Btooom on this island with their lives at stake. Ryouta must use tactics to prevail in this battle of life and death.

35. Grimgar: Ashes and Illusions (Hai to Gensou no Grimgar)

isekai anime with op mc

The story revolves around a group of teenagers who find themselves thrown into a fantasy world called Grimgar, similar to virtual reality games, but the only difference is that there are no redos in this parallel world.

MC Haruhiro is a guy with a quiet personality. He forms a party with other teenagers who are left alone because of their weak powers. They end up creating a party to fight various monsters ranging from goblins to dragons. Haruhiro must cooperate with other party members to survive in this world where death is roaming around everywhere.

34. Sword Art Online

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Kazuto Kirigaya likes to test out new games and tech stuff. He participated in the beta test of Sword Art Online, the first virtual reality MMORPG game.

Upon official release, Kazuto dives into the game only to find that the game creator has disabled the log-out option until one of them clears the game. In addition, dying in this game results in death in the real-life world.

He decides to clear the game as a solo player because he can’t afford to take responsibility for party members’ lives. Kazuto’s knowledge and powers might not be enough to clear the game. Some people argue that SAO is not isekai, but some of the series’ themes suggest otherwise.

33. Wise Man’s Grandchild

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Shin Wolford is the adopted son of Merlin Wolford. He is the reincarnation of an ordinary Japanese man who died in a tragic accident. Shin acquires a great aptitude for magic and martial arts.

Using his past world knowledge, he managed to master magic spells at an early age. Shin develops his own destructive magic spell that makes him overpowered. However, he fails to develop a sense of responsibility, so his stepfather made him attend the magic academy of this world.

Shin must make new friends while gaining maturity and social skills. However, his overpowered skills might drag him into unusual problems more than he imagined.

See recommended: 15 Animes Like Wise Man’s Grandchild with MC in a Magical World!

32. Gate: Jieitai Kanochi nite, Kaku Tatakaeri

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Next on our list is a military theme isekai anime. On a peaceful day, Japan is attacked by outwardly monsters and warriors. They managed to invade Japan by using a mysterious portal that connects to a parallel world. With the government’s swift actions, they managed to minimize the casualties.

Youji Itami is a guy obsessed with otaku culture working in special forces. He played a significant role in saving people during the invasion. Later, he gets tasked with exploring the world beyond the gate with some other officers. He must operate with caution because a single mistake can provoke a war between two worlds.

31. Hack//SIGN

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Our protagonist is Tsukasa, a young guy with a gloomy personality. Upon waking up, he finds himself in another world. He suffers from amnesia and doesn’t know much about himself. He is accompanied by a strange cat called Macha.

Tsukasa gets to know that he is trapped in a virtual reality game through a series of events, and the log-out option is nowhere to be found. He must work together with the people in this world to learn more about himself while finding a way back.

30. Skeleton Knight in Another World

isekao anime with op mc Skeleton Knight in Another World

A gamer falls asleep playing video games, only to wake up in the game world as a skeleton named Arc. Shrouded in a daunting avatar and desperately seeking anonymity, he is thrust into an unfamiliar fantastical land.

His attempts of leading a peaceful existence are short-lived when he meets Ariane–a beautiful warrior intent on sending him off on a tumultuous journey full of conflict and excitement.

29. Isekai wa Smartphone to Tomo ni. (In Another World with my Smartphone)

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Touya Mochizuki is a young guy with a kind personality. One day, he is suddenly struck by lightning as God made a mistake. To compensate, he gave him a luxurious life in a fantasy world and even allowed him to take his smartphone to this world.

Touya discovers that he has great potential for magic, which means that the MC is OP. He decides to enjoy this life as much as possible with this new life. Touya might change the lives of people around him for better or worse.

28. Dog Days

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Dog Days is a fantasy isekai anime that features the transition of an average human to another world full of magic and wonders.

Cinque Izumi is a teenage guy studying in middle-high school. He had a sturdy body thanks to his love for sports. Millhiore, the princess of the Biscotti Kingdom, summons him to fight a war with a neighboring country.

Upon reaching this world, Cinque receives a powerful sacred weapon called Palladion that makes him overpowered.

He must participate in the war as a knight of the Biscotti Kingdom. Fortunately, battles in this world are similar to sports, and Cinque excels in them.

27. Re:Zero − Starting Life in Another World

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Subaru Natsuki would like to avoid trouble as much as possible. One day, he suddenly finds himself transported to another world only to be beaten by some thugs. He is saved by a girl named Stella. Subaru and Satella are murdered, but things don’t end here as he finds himself back in time to the starting point with the same scenario.

With this strange situation in place, Subaru must operate with caution as things are likely to go crazy with one unaccounted moment.

26. Magic Knight Rayearth

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On a fateful day, three girls met each other at Tokyo Tower as a mere coincidence. Before they can introduce each other, they are swept by a flying monster fish that takes them to another world.

Our main characters are Hikaru Shidou, Umi Ryuuzaki, and the lovely girl with glasses Fuu Houoji, who find themselves in a fantasy world called Cephiro.

A man named Clef tells them that they are destined to become Magic Knights that will save the princess of Cephiro from the constraints of an evil priest. They must save the princess and this world by becoming warriors of justice.

25. Demon Lord, Retry! (Maou-sama, Retry!)

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MC Hakuto Kunai is an overpowered demon lord living in a fantasy world. His consciousness belongs to a middle-aged Japanese man who created Infinity’s game.

Through a series of events, he finds himself in the body of Hakuto, who is the last boss of his game. He saves a cute girl named Aku from a demon and ends up taking care of her. Hakuto is troubled to find that this world had monsters and demons, although he didn’t create any of those in his game.

Troubled by this strange situation, He decides to explore the horizons of this world while enjoying the perks of being an overpowered demon lord.

24. Outbreak Company

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Shinichi Kanou is a young man with an otaku lifestyle. One day, out of frustration, he applied for a decent job only to find himself transported to a fantasy world.

Through a series of events, He finds that the Japanese government has selected him as their ambassador, and he has only one job, which is to promote otaku culture in this fantasy world. Shinichi had to educate the people of the Eldant Empire about the modern world and things like manga, anime, and games.

At first, he finds this job easy, but gradually Shinichi learns that promoting otaku culture is way more complex than he imagined.

23. Ascendance of a Bookworm 

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Honzuki no Gekokujou is a slice-of-life Isekai anime that features the reincarnation of a girl obsessed with literature and books in a fantasy world.

Motosu Urano, a lady who is an avid reader. She had a large collection of books in her home. However, just when she is about to get her dream job in a library, an earthquake strikes her living area, and she dies getting buried by her books. Later, she finds herself reincarnated in the body of a small girl named Myne, a commoner girl living in the medieval era.

Upon gaining consciousness, she rushes to find some books, but to her shock, books are expensive items in this world, and only nobles can afford them. Myne must find a way to fulfill her thirst for books.

22. So I’m a Spider, So What? (Kumo Desu ga, Nani ka?)

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In this Isekai anime, the OP MC is Kumoko, an introverted girl living a lonely life as a shut-in gamer. She musters the courage to attend high school, but a catastrophe strikes her high school killing everyone. Thanks to a miraculous light, she was fortunate enough to get reincarnated along with some fellows.

However, unlike her classmates, Kumoko is reincarnated as a low-level spider, but she decides to level up by striving so that she can achieve a luxurious life. Sometime later, She reaches a high level and becomes overpowered to the point that everyone begins to fear her. Kumoko might get to live her long-desired life very soon.

21. The Devil is a Part-Timer! (Hataraku Maou-Sama!)

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Our powerful purple hair anime protagonist is Sadao Maou, an overpowered demon lord who plans to conquer the magical world of Ente Isla. However, his plan is spoiled by the interference of Emilia, a hero with divine powers. He escapes the battleground along with his subordinate through a portal that transfers him to the human world.

Upon reaching this world, He loses all his magic powers, much to his dismay. Maou lives a normal life until they find a way back to their original homeland. However, he is followed by Emilia into this world, so he cannot expect to live a carefree life.

20. The Seven Deadly Sins (Nanatsu no Taizai)

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16. Nanatsu no Taizai

“The Seven Sins” is the name of a group of powerful knights who plotted to overthrow the British kingdom.

Rumor has it that the holy knights destroyed every trace of the seven sins and none of them survived. Now, the holy knights are plotting a military coup to take over the kingdom.

Elizabeth Liones, the third beautiful princess of Liones Kingdom, embarks on a quest to find the seven sins to help her. Her journey begins in a small pub run by Meliodas.

19. InuYasha

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Kagome Higurashi is a cute girl studying in middle-high school. Her family owns a shrine called Shinto Shrine. A demon throws her in a well through a series of events that takes her back in time.

Upon waking, she finds herself in the Sengoku Era, where warlords are fighting each other for territory. She receives a powerful necklace embedded with jewels that can grant the user’s wish. However, a battle with a demon causes the jewels to scatter around.

She meets our main character, Inuyasha, a demon dog and human hybrid who holds command over an overpowered sword. Together, they must find the scattered jewel before they fall into the hands of a demon.

18. The Twelve Kingdoms

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Youko Nakajima is a young girl with red hair that fails to make friends because her fellows deemed her ugly. She always ends up running errands for others because of her kind personality.

One day, A man named Keiki appears in front of her from a parallel world and claims her to be the heir of his kingdom. Suddenly, they are interrupted by the attack of demons called Youma. Keiki saves her by taking her into his world.

Youko finds herself alone upon waking up because the earlier attack separated her from Keiki. She now must navigate through this world without falling prey to the schemes of evil people.

17. Saga of Tanya The Evil

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Tanya Degurechaff is a little girl serving in the military of the Fatherland Reich Empire. On the surface, she is no different from an innocent girl with a kind nature, but in reality, she is an evil mean heartless crazy girl.

Tanya is the reincarnation of an ordinary Japanese worker who refused to accept the existence of God even on the brink of death. God made him a small girl in an alternate world as a challenge.

Despite witnessing the power of God, Tanya still strives to prove that there is no such thing as God while unintentionally making her Empire the most potent in the world.

16. Ixion Saga DT

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Our MC is Kon Hokaze in of the most fun isekai anime on this list. He is a guy obsessed with games. Upon accepting a quest request from an unknown user, he finds himself transported to another world similar to a game.

He acquires a mighty sword called Alma Gear, which can harness mysterious energy called Alma. Kon saves the princesses of this world from a group of attackers only to find himself in much greater trouble as the princesses appointed him as her guard.

Kon must protect her during the journey while finding a way back. He might end up using his new powers to fight various deadly foes that await him.

15. Arifureta: From Commonplace to World’s Strongest

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Hajime Nagumo is a guy with a shy personality. He was always the target of bullies in high school. When his entire class gets transported to a parallel world, he hopes for a good life there, but he again gets bad treatment there because of his weak power. Hajime falls into the labyrinth’s depths during a labyrinth exploration as one of his fellows betrays him.

Desperate to get revenge, he feeds on the monsters’ flesh and now the badass MC becomes overpowered. With this new power in hand, Hajime decides to climb up the ranks of this world as the world’s strongest man.

See recommended: 23 Isekai Anime Like Arifureta

14. Cautious Hero: The Hero Is Overpowered but Overly Cautious

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12. Cautious Hero: The Hero Is Overpowered but Overly Cautious

Goddesses are tasked with summoning heroes from parallel worlds to save different worlds from destruction. Our MC is Seiya Ryuuguuin, a handsome guy with long hair from the earth. He gets summoned by goddess Ristarte to save the world of Gaeabrande from the demon lord’s army.

She is happy to discover that Seiya is an overpowered guy, but soon she finds that he is highly cautious and wastes a lot of time training to defeat even low-level demons.

The demon lord ruling this world is quite powerful as he managed to conquer this world in a short amount of time. Seiya’s cautiousness might initially feel troubling, but it might be perfect for saving this world.

13. How Not to Summon a Demon Lord (Isekai Maou to Shoukan Shoujo no Dorei Majutsu)

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How Not to Summon a Demon Lord is an Isekai harem anime. Takuma Sakamoto, The MC, is a young guy who has abandoned his reality to submerge himself in a virtual reality game called Cross Reverie. He is the overpowered demon lord named Diablo with all rare spells and artifacts in-game.

Upon summoning, he finds himself in the world of the game. Diablo meets Shera and Rem, two cute girls who have summoned him to aid them. With this situation in place, Diablo sets out to explore this world and make them tremble in fear as the overpowered demon lord.

12. Isekai Izakaya: Japanese Food From Another World

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Our main character is Nobuyuki Yazawa, a skilled chef who owns a traditional Japanese bar. He works alongside Shinobu Senke, a teenage girl passionate about cooking. Together, they serve various customers that are in love with their mouth-watering dishes.

In addition to regular customers, they also open their bar to the residents of a parallel world living in a city called Aitheria. Nobuyuki must make more delicious dishes so that his customers from both worlds keep coming back to their small yet unique bar.

11. Kage no Jitsuryokusha ni Naritakute!

isekai anime op mc Kage no Jitsuryokusha ni Naritakute!

In his previous life, Minoru Kagenou has been fixated on becoming as strong as possible, but he couldn’t accomplish much at all. But now after being reborn into a magical world full of possibilities he’s now striving to reach the impossible. With the power he so desired finally within his grasp, He is determined to recruit members into his fake organization the Shadow Gardenis, to take down the mysterious cult that lurks in the shadow.

10. Tensai Ouji no Akaji (The Genius Prince’s Guide to Raising a Nation Out of Debt)

isekai anime with op mc Tensai Ouji no Akaji

The King of Natra has been taken ill, leaving the fate of his kingdom to the only heir, Prince Wein Salema Arbalest. Despite his intelligence, Wein’s innermost desire is to flee and enjoy a life free from responsibility. Sadly for him, matters take a turn for the worse when he receives an invitation to a trap, leading to trouble with an encroaching western kingdom. Forced to face tricky opponents on multiple fronts and even his former best friend leading a rebel army, he eventually makes his way home.

Had Wein fully committed to using his OP abilities, he could have easily turned this into a lengthy anime series consisting of military conquest and occupation stretched over 2-3 seasons through various manipulations around the world. The only one able to keep up with him is Ninym; an unofficial aide and comrade with white hair from a race heavily ostracized by the ‘civilized’ world. Thankfully, though, we’re spared such an ending as he chooses instead to reject such ambition in favor of lazing about and hiding much of what he’s capable of.

9. No Game, No Life

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A parallel world named Disboard is ruled by one God named Tet, who oversees the matters of this vast world. Almost all kinds of races live in this world, but Humans are considered weak because of their inability to use magic properly.

However, things begin to change when Tet finds our protagonists, Sora and Shiro, who are stepsiblings renowned in the gaming world because of their supreme skills.

Upon clicking on an invite sent by Tet, they find themselves transported to the world of Disboard. With this situation in place, Shiro and Sora must use their overpowered tactical skills to conquer this new world while finding a way back home.

8. Death March to the Parallel World Rhapsody

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Ichirou Suzuki is a middle-aged man working as a programmer. He spends each day working on various projects until he passes out. On one of his typical days, Ichirou passes out while debugging a game only to get transported to a game-like world. Moreover, his appearance has changed from his younger self.

He destroys an army of monsters by using one of his basic skills. He gains an insane increase in level and power, making him overpowered right off the bat. Ichirou must find the root cause behind his transportation while enjoying a youthful life in this world.

See recommended: 25 Best Anime Like Death March Kara Hajimaru Isekai Kyousoukyoku

7. The Misfit of Demon King Academy

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In the beginning, demons, angels, and humans lived together in a single realm, but a fierce war broke out between them, and the demon lord sacrificed his life to divide this single realm into three domains to end the war.

Our main character is Anos Voldigoad, the reincarnation of the late demon king. Upon awakening, he visits the demon world only to discover that his name and past have been tampered with, and people worship the name of another fake demon lord.

He decides to enroll at the Demon King Academy to find the culprits. Anos might end up using his overpowered abilities to reclaim his throne.

See recommended: 40 Anime Where The Mc is Op but Hises But Hides His Power

6. Isekai no Seikishi Monogatari

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Kenshi Masaki is a young guy skilled in martial arts. He has unparalleled strength and stamina that makes him overpowered. Through a series of events, Kenshi is kidnapped by a group of shady people.

Upon awakening, he finds himself in a parallel world called Geminar. They made him pilot an advanced robot called Sacred Mechanoid to fight the royal army. Although they lost the battle, Lashara, the princess of this world, let him live by making him join the royal army. Kenshi must fight strategically to survive in this world.

5. The Rising of the Shield Hero

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Naofumi Iwatanithe was summoned to a parallel world along with three other people to become world heroes. Each of the heroes is equipped with a legendary tool Neopomi received the legendary shield as his weapon and the rest received a bow, sword, and spear.

Due to the lack of experience and charisma and the fact that he can only use the shield, Naofumi’s weapon is considered the weakest of them all.

Eventually betrayed, the MC OP is charged with a crime he did not commit and deported on the third day of his journey. When he was ostracized by everyone, Naofumi’s thoughts were filled with hatred and revenge.

Thus, his destiny in the parallel world begins and as a result, he becomes so OP as his character is strengthened by the humiliation.

4. Jobless Reincarnation: I Will Seriously Try If I Go To Another World

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Here is an Isekai adventure anime that features a shut-in gamer who dies in an attempt to save a bunch of guys from a truck only to be reincarnated as a young guy in a fantasy world.

Our protagonist is Rudeus Greyrat, a young kid living in a fantasy world. In his past life, he was a shut-in old gamer. He sacrifices his life to save a bunch of idiots and reincarnates into a magical world. With this new chance, Rudeus decides to give him all so that he can live a life without any regrets.

Moreover, his new parents are loving and caring. Using his past knowledge, he gains a strong command of magic that made him overpowered at a very young age, much to everyone’s surprise.

3. KonoSuba: God’s Blessing on This Wonderful World!

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An Isekai anime that features a lame otaku guy who dies pathetically only to be reincarnated in a new fantasy world.

Our protagonist is Kazuma Satou, a teenager living a miserable life. He dies a laughable death despite trying to save a girl.

Upon reincarnating in the new world, he finds himself loaded with many problems as he takes the goddess Aqua with him, who is nothing but useless in all circumstances. Moreover, this new world is nothing like easy games as they have to work hard to survive and earn daily bread.

With this bizarre situation in place, Kazuma must strive to stay rational as everything around him is bound to go crazy.

2. Overlord

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Searching for an action Isekai anime with an OP MC? Overlord will satisfy your binge craze. Momonga is a guy who has been playing a virtual reality game called Yggdrasil for a long time. His character has no flesh on his body which makes him quite terrifying. He holds supreme command over dark magic, which makes him overpowered.

However, the game developers decided to close the servers of this game for unknown reasons, but Momonga chooses to enjoy the last moments with his guild members only to find himself stuck in this game.

The world and people around him have completely changed. With this situation in place, Momonga sets out on a journey to explore the horizons of this new world.

1. That Time I Got Reincarnated as a Slime

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Tensei Shitara Slime Datta Ken is an Isekai fantasy anime featuring a middle-aged guy who dies in a random accident only to be reincarnated as a slime in a fantasy world.

Our MC is Satoru Mikami, a middle-aged guy working in an agency. He lived a lonely life until he died at the hands of a random robber. Soon, he finds himself reincarnated in a parallel fantasy world as a slime. He gains a bunch of skills by killing some monsters. He meets Veldora, the legendary storm dragon, and becomes friends with him.

Veldora gives him a new name Rimuru Tempest which made him overpowered. Rimuru decides to explore the horizons of this new world while finding a way to break the robust seal that imprisons Veldora.

See also: The Ultimate List Of Best Manga With Overpowered Main Character

I have been an anime fan for as long as I can remember, and I love writing articles.